Pericholangitis with Ulcerative Colitis Following Autoimmune Hepatitis over 12 Years

Seiko CHUJO; Choitsu SAKAMOTO; Shigekazu OHNO; Shinsuke MORIMOTO; Masaki MIYAMOTO; Hiroyuki OKANO; Sumiharu MORITA; Susumu SAEKI; Munetada OIMOMI; Takahiro FUJIMORI; Sakan MAEDA; Masato KASUGA

doi:10.2169/internalmedicine.31.1228

Seiko CHUJO, Choitsu SAKAMOTO, Shigekazu OHNO, Shinsuke MORIMOTO, Masaki MIYAMOTO, Hiroyuki OKANO, Sumiharu MORITA, Susumu SAEKI, Munetada OIMOMI, Takahiro FUJIMORI, Sakan MAEDA, Masato KASUGA

Author information

Seiko CHUJO
the Second Department of Internal Medicine, Kobe University School of Medicine
Choitsu SAKAMOTO
the Second Department of Internal Medicine, Kobe University School of Medicine
Shigekazu OHNO
the Second Department of Internal Medicine, Kobe University School of Medicine
Shinsuke MORIMOTO
the Second Department of Internal Medicine, Kobe University School of Medicine
Masaki MIYAMOTO
the Second Department of Internal Medicine, Kobe University School of Medicine
Hiroyuki OKANO
the Second Department of Internal Medicine, Kobe University School of Medicine
Sumiharu MORITA
the Second Department of Internal Medicine, Kobe University School of Medicine
Susumu SAEKI
the Second Department of Internal Medicine, Kobe University School of Medicine
Munetada OIMOMI
the Second Department of Internal Medicine, Kobe University School of Medicine
Takahiro FUJIMORI
the Second Department of Pathology, Kobe University School of Medicine
Sakan MAEDA
the Second Department of Pathology, Kobe University School of Medicine
Masato KASUGA
the Second Department of Internal Medicine, Kobe University School of Medicine

Keywords: liver biopsy, colonoscopy, ERCP

JOURNAL FREE ACCESS

1992 Volume 31 Issue 10 Pages 1228-1232

DOI https://doi.org/10.2169/internalmedicine.31.1228

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Abstract

A 35-year-old woman was diagnosed as autoimmune hepatitis 12 years ago by abnormal findings of liver tests including lupus erythematosus (LE) cell phenomenon and liver biopsy. She was admitted in May 1990 with a history of lower gastrointestinal bleeding. Colonoscopy with biopsy and barium enema revealed chronic ulcerative colitis along the entir colon. Since liver tests did not respond well to prednisolone treatment, liver biopsy was again performed and it revealed periductal inflammation with small duct proliferation, a finding compatible with pericholangitis. We herein report this patient who was initially diagnosed as autoimmune hepatitis and thereafter found to be pericholangitis associated with ulcerative colitis.
(Internal Medicine 31: 1228-1232, 1992)

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