Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Studies on 1-Alkyl-2 (1H)-pyridone Derivatives. XXII. The Friedel-Crafts Reaction of 1-Methyl-2 (1H)-pyridone and Its Homologs with Benzoyl Chloride
HIROSHI TOMISAWAREIKO FUJITAHIROSHI HONGOHIDEKI KATO
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1974 Volume 22 Issue 9 Pages 2091-2096

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Abstract
The Friedel-Crafts reaction of 1-methyl-2 (1H)-pyridone (I), 1-methyl-2 (1H)-quinolone (II), and 2-methyl-1 (2H)-isoquinolone (III) with benzoyl chloride was successfully carried out. I gave products identified as 5-benzoyl-1-methyl-2 (1H)-pyridone (IV), 3-benzoyl-1-methyl-2 (1H)-pyridone (V), and 3, 5-dibenzoyl-1-methyl-2 (1H)-pyridone (VI). II gave 3-benzoyl-1-methyl-2 (1H)-quinolone (VII) and 6-benzoyl-1-methyl-2 (1H)-quinolone (VIII), and III gave 4-benzoyl-2-methyl-1 (2H)-isoquinolone (IX) and 5-benzoyl-2-methyl-1 (2H)-isoquinolone (X).
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