3-Amino-5-bromo-2-hydroxypyridine (II) was successfully converted to 2-substituted 6-bromoxazolo [5, 4-b] pyridines by treatment with acetic anhydride, benzoic anhydride, or potassium methylxanthate and some of their properties were examined. An attempt to obtain 2-amino-6-bromoxazolo [5, 4-b] pyridine by the application of cyanogen bromide to (II) ended fruitless and only (5-bromo-2-hydroxy-3-pyridyl) urea was obtained.