The development of advanced computational methods used for predicting performance lifetimes of materials exposed to harsh radiation environments are highly dependent on fundamental understanding of solid-radiation interactions that occur within metal components. In this work, we present successive and concurrent in situ TEM dual-beam self-ion irradiation of 2.8 MeV Au⁴⁺ and implantation of 10 keV He¹⁺, utilizing a new facility at Sandia National Laboratories. These experiments, using a model material system, provide direct real-time insight into initial interactions of displacement damage and fission products that simulate damage from neutron exposure. In successive irradiation, extensive dislocation loop and stacking fault tetrahedra damage was formed and could be associated with individual ion strikes, but no evidence of cavity formation was observed. In contrast, concurrent irradiation to the same dose resulted in the onset of cavity formation at the site of a heavy-ion strike. This direct real-time observation provides insight into the complex interplay between the helium and vacancy dynamics.