Excellent Thermal Control Ability of Cell Biology Experiment Facility (CBEF) for Ground-Based Experiments and Experiments Onboard the Kibo Japanese Experiment Module of International Space Station

Sachiko Yano; Daisuke Masuda; Haruo Kasahara; Katsunori Omori; Akira Higashibata; Makoto Asashima; Takeo Ohnishi; Fumio Yatagai; Seiichiro Kamisaka; Toshiharu Furusawa; Atsushi Higashitani; Hideyuki J. Majima; Takeshi Nikawa; Kazuyuki Wakabayashi; Hideyuki Takahashi; Hiromi Suzuki; Toru Shimazu; Keiji Fukui; Atsuhiko Hattori; Fumiaki Tanigaki; Masaki Shirakawa; Tai Nakamura; Yoshinori Yoshimura; Nobuo Suzuki; Noriaki Ishioka

doi:10.2187/bss.26.12

Original Papers

Excellent Thermal Control Ability of Cell Biology Experiment Facility (CBEF) for Ground-Based Experiments and Experiments Onboard the Kibo Japanese Experiment Module of International Space Station

Sachiko Yano, Daisuke Masuda, Haruo Kasahara, Katsunori Omori, Akira Higashibata, Makoto Asashima, Takeo Ohnishi, Fumio Yatagai, Seiichiro Kamisaka, Toshiharu Furusawa, Atsushi Higashitani, Hideyuki J. Majima, Takeshi Nikawa, Kazuyuki Wakabayashi, Hideyuki Takahashi, Hiromi Suzuki, Toru Shimazu, Keiji Fukui, Atsuhiko Hattori, Fumiaki Tanigaki, Masaki Shirakawa, Tai Nakamura, Yoshinori Yoshimura, Nobuo Suzuki, Noriaki Ishioka

Author information

Sachiko Yano
Japan Aerospace Exploration Agency
Noto Marine Laboratory, Institute of Nature and Environmental Technology, Kanazawa University
Daisuke Masuda
Japan Manned Space Systems Corp.
Haruo Kasahara
Japan Manned Space Systems Corp.
Katsunori Omori
Faculty of Economics, Asia University
Akira Higashibata
Japan Aerospace Exploration Agency
Makoto Asashima
Research Center for Stem Cell Engineering, National Institute of Advanced Industrial Science and Technology
Takeo Ohnishi
Department of Radiation Oncology, School of Medicine, Nara Medical University
Fumio Yatagai
Computational Astrophysics Laboratory, The Institute of Physical and Chemical Research (RIKEN)
Seiichiro Kamisaka
Department of Biology, Graduate School of Science and Engineering, University of Toyama
Toshiharu Furusawa
Department of Applied Biology, Faculty of Textile Science, Kyoto Institute of Technology
Atsushi Higashitani
Graduate School of Life Sciences, Tohoku University
Hideyuki J. Majima
Department of Oncology and Space Environmental Medicine, Kagoshima University Graduate School of Medical and Dental Sciences
Takeshi Nikawa
Department of Nutritional Physiology, Institute of Health Biosciences, The University of Tokushima Graduate School
Kazuyuki Wakabayashi
Department of Biological Sciences, Graduate School of Science, Osaka City University
Hideyuki Takahashi
Graduate School of Life Sciences, Tohoku University
Hiromi Suzuki
Japan Space Forum
Toru Shimazu
Japan Space Forum
Keiji Fukui
Japan Space Forum
Atsuhiko Hattori
Department of Biology, College of Liberal Arts and Sciences, Tokyo Medical and Dental University
Fumiaki Tanigaki
Japan Aerospace Exploration Agency
Masaki Shirakawa
Japan Aerospace Exploration Agency
Tai Nakamura
Japan Aerospace Exploration Agency
Yoshinori Yoshimura
Japan Aerospace Exploration Agency
Nobuo Suzuki
Noto Marine Laboratory, Institute of Nature and Environmental Technology, Kanazawa University
Noriaki Ishioka
Japan Aerospace Exploration Agency

Keywords: JAXA Hardware, Microgravity, Life Science, Cell Culture

JOURNAL FREE ACCESS

2012 Volume 26 Pages 12-20

DOI https://doi.org/10.2187/bss.26.12

Details

Abstract

The Japan Aerospace Exploration Agency (JAXA) has been developing several life science hardware components for the Japanese experiment module ‘Kibo’ in the International Space Station (ISS). The Cell Biology Experiment Facility (CBEF) is one of these. It contains an environmental control system to regulate variables such as the temperature and humidity. It is also equipped with a centrifuge and has the ability to culture bio-specimens in a temperature range of 15 to 40°C. In biological experiments that include in vitro cell culture, temperature control is a key factor in the success of the experiment. Thus, we first examined the temperature data in the CBEF on the ground while changing the room temperature and cooling water temperature to investigate the ability of the CBEF. Based on the ground experiment data, we carried out life science experiments onboard Kibo. Judging from the temperature data in the CBEF under microgravity, 12 life science experiments were successfully conducted up until 2011. Considering our present data, we strongly believe that the CBEF is a functional incubator in the ISS and will contribute to future experiments.

Corresponding author

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