We report here the rare case of extramedullary plasmacytoma of the larynx in a 74 year-old female which recurred 4 times. She first visited our clinic complaining of hoarseness on Jun 12,1997. The appearance of the tumor was like a polyp in left vocal cord. Initially, we had instituted treatment for a polyp, and it was resected by a direct laryngomicrosurgery. One month after the first surgery, a local recurrence was found and was resected by CO₂laser. However two other recurrences were found.
The histological examination by HE staining was of chronic inflammation and on extramedullary plasmacytoma. The plasmacytoma (IgG, λtype) was detected using by immunoperoxidase staining.
Our current strategy is local treatment for a polypoid lesion. However, further recurrences could require a laryngofissure operation for complete resection of the lesion.