Third Ventriculostomy in Late-onset Idiopathic Aqueductal Stenosis Treatment: A Focus on Clinical Presentation and Radiological Diagnosis

Marco LOCATELLI; Riccardo DRAGHI; Andrea DI CRISTOFORI; Giorgio CARRABBA; Mario ZAVANONE; Mauro PLUDERI; Diego SPAGNOLI; Paolo RAMPINI

doi:10.2176/nmc.oa.2013-0367

Original Articles

Third Ventriculostomy in Late-onset Idiopathic Aqueductal Stenosis Treatment: A Focus on Clinical Presentation and Radiological Diagnosis

Marco LOCATELLI, Riccardo DRAGHI, Andrea DI CRISTOFORI, Giorgio CARRABBA, Mario ZAVANONE, Mauro PLUDERI, Diego SPAGNOLI, Paolo RAMPINI

Author information

Marco LOCATELLI
Neurosurgery Unit, Fondazione I.R.C.C.S. “Ca’ Granda” Ospedale Maggiore Policlinico
Riccardo DRAGHI
Neurosurgery Unit, Fondazione I.R.C.C.S. “Ca’ Granda” Ospedale Maggiore Policlinico
Neurosurgery Unit, Department of Medical and Surgical Pathophysiology of Organs and Transplantation, Università degli Studi di Milano
Andrea DI CRISTOFORI
Neurosurgery Unit, Fondazione I.R.C.C.S. “Ca’ Granda” Ospedale Maggiore Policlinico
Neurosurgery Unit, Department of Medical and Surgical Pathophysiology of Organs and Transplantation, Università degli Studi di Milano
Giorgio CARRABBA
Neurosurgery Unit, Fondazione I.R.C.C.S. “Ca’ Granda” Ospedale Maggiore Policlinico
Mario ZAVANONE
Neurosurgery Unit, Fondazione I.R.C.C.S. “Ca’ Granda” Ospedale Maggiore Policlinico
Neurosurgery Unit, Department of Medical and Surgical Pathophysiology of Organs and Transplantation, Università degli Studi di Milano
Mauro PLUDERI
Neurosurgery Unit, Fondazione I.R.C.C.S. “Ca’ Granda” Ospedale Maggiore Policlinico
Diego SPAGNOLI
Neurosurgery Unit, Ospedale Generale “Moriggia-Pelascini”
Paolo RAMPINI
Neurosurgery Unit, Fondazione I.R.C.C.S. “Ca’ Granda” Ospedale Maggiore Policlinico

Keywords: hydrocephalus, late-onset idiopathic aqueductal stenosis, third ventriculostomy, endoscope

JOURNAL OPEN ACCESS

2014 Volume 54 Issue 12 Pages 1014-1021

DOI https://doi.org/10.2176/nmc.oa.2013-0367

Browse “Advance online publication” version

Details

Abstract

Endoscopic third ventriculostomy (ETV) is considered the gold standard treatment for obstructive hydrocephalus due to partial or complete obstruction of cerebrospinal fluid (CSF) ventricular pathways caused by mass lesions. However long-term efficacy of this procedure remains controversial as treatment of chronic adult hydrocephalus due to stenosis of Sylvian acqueduct [late-onset idiopathic aqueductal stenosis (LIAS)]. The authors describe clinical presentation, diagnostic investigations in patients affected by LIAS, and define their clinical and radiological outcome after ETV. From January 2003 to December 2008, 13 consecutive LIAS patients treated by ETV were retrospectively reviewed. Pre- and post-operative clinical and radiological findings, including conventional and phase-contrast (PC) cine magnetic resonance imaging (MRI) were investigated. ETV was successfully performed in all patients. Patient’s neurological condition improved. No one required a second ETV procedure or shunt implantation. Clinical and radiological results reveal a satisfactory outcome of LIAS patients treated by ETV. At follow-up a clinical improvement could be demonstrated in all cases. Selection criteria of LIAS patients seem to be crucial to obtain satisfactory and long-lasting results. Even in elderly patients with chronic hydrocephalus, ETV can be considered the treatment of choice.

Corresponding author

Register with J-STAGE for free!