Progress of Digestive Endoscopy
Online ISSN : 2187-4999
Print ISSN : 1348-9844
ISSN-L : 1348-9844
症例
胃過形成性ポリープに乳頭腺癌と印環細胞癌がみられた1例
花井 将彰星野 洋一町田 守也大木 一郎栗原 照昌高橋 厚山田 勲荒井 剛宮本 幸男東郷 庸史吉松 弘
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2003 年 62 巻 2 号 p. 78-79

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A 58-year-old female was referred to our hospital for endoscopic gatric polypectomy in January, 2002. Endoscopic examination revealed Yamada type IV polyp, 4.5cm in length, on the posterior wall of the middle gastric body. Histological findings of the polypectomied specimen suggested a hyperplastic polyp with cells of papillary adenocarcinoma and signet ring cell carcinoma, respectively, in the polyp. The phenotype of the carcinoma in the polyp was evaluated by immunohistochemicaly with CD10, MUC2 and human gastric mucin (HGM) . The carcinoma and the hyperplastic foveolar epithelium were only positive for HGM. Therefore the carcinoma was classified as gastric type. It is said that this type changed more commonly to undifferentiated type during the course of invasion of the mucosa and/or the submucosa or deeper. This case was thought to be very rare in that signet ring cell carcinoma and papillary adenocarcinoma were developing in a hyperplastic polyp in the stomach.

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© 2003 一般社団法人 日本消化器内視鏡学会 関東支部
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