A 54-year old man underwent gastro-intestinal endoscopy, which detected carcinoma and varices (F3 grade) in his esophagus simultaneously. Endoscopic sclerotherapy and band ligation were carried out in the treatment for esophageal varices initially. Since we could not achieve subsequent endoscopic mucosal resection at carcinoma because of mucosal changes after varices treatment, other therapy, such as radiation and chemotherapy, were employed. However, twice recurrences of esophageal cancer within seven months were observed, and we tried a photo dynamic therapy, resulting in two years recurrence free so far. The treatment of esophageal cancer with F3 grade varices should be further discussed.
