A 69-years old man was diagnosed as esophageal malignant lymphoma by regular endoscopic GI check up. Endoscopy showed small submucosal tumor in lower esophagus. EUS revealed low echoic tumor in lpm-sm layer. Three courses of chemotherapy (CHOP) was given from June 1999 to September 1999. The tumor showed no remarkable change in size by endoscopy and EUS after chemotherapy. We performed EMR of the lesion and the pathological finding showed that most of this elevated lesion was consisted of fibrosis and inflamatoric cell, but still there existed a certain amount of viable tumor cells at the edge of the specimen thus we added radiation therapy. In this case, EMR seems to be critical for not only treatment but also the accurate evaluation of chemotherapy.