Characterization of Antibody Response to Pseudomonas aeruginosa in Patients with Wound Infections

Elzbieta Anna TRAFNY; Jacek GRZYBOWSKI; Jan PATZER; Danuta POPIEL; Jolanta WREMBEL-WARGOCKA; Danuta DZIERZANOWSKA; Irena ZAWISTOWSKA-MARCINIAK; Kazimierz KOBUS

Characterization of Antibody Response to Pseudomonas aeruginosa in Patients with Wound Infections

Elzbieta Anna TRAFNY, Jacek GRZYBOWSKI, Jan PATZER, Danuta POPIEL, Jolanta WREMBEL-WARGOCKA, Danuta DZIERZANOWSKA, Irena ZAWISTOWSKA-MARCINIAK, Kazimierz KOBUS

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JOURNAL FREE ACCESS

1991 Volume 35 Issue 6 Pages 435-442

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Abstract

ELISA was used to measure the amount and avidity of IgG antibodies to exotoxin A (ExA) and 7 Fisher's immunotypes of lipopolysaccharide (LPS) in the sera of 13 patients with mild or moderate Pseudomonas aeruginosa infections. Changes in the specificity of tested sera during the course of infection were demonstrated. A statistically significant increase was seen in the amount and avidity of the antibodies to ExA in a majority of the sera, and an increase was seen in amount of antibodies to LPS immunotype 4 in the sera of patients with moderate infections.

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