One hundred ten cases of odontogenic tumors histologically diagnosed according to the WHO classification (1992) were clinicostatistically evaluated at our clinic over the 23-year period from 1973 to 1996.
The subjects consisted of 55 men and 55 women 40 to 80 years old.
Histologically, the 107 benign tumors comprised 37 ameloblastomas, 36 compound odontomas, 20 complex odontomas, 4 calcifying odontogenic cysts, 3 odontogenic fibromas, 3 odontogenic myxomas, 2 ameloblastic fibro-odontomas, 1 adenomatoid odontogenic tumor, and 1 benign cementoblastoma. The 3 malignant tumors consisted of 2 primary intraosseous carcinomas and 1 malignant ameloblastoma.
Most of the ameloblastomas occurred in the posterior portion of mandible, and many odontomas occurred in the incisor region of both the maxilla and the mandible.
All tumors were treated surgically, and various of procedures were used.
All three odontogenic carcinomas spread extensively throughout the mandible. There has been no evidence of disease in one patient, one patient died of the oral carcinoma, and the other patient died of lung metastasis.