Serum viscosity is an important physical property for the simulation of solutetransfer in hemodialysis. For normal serum, its viscosity can be estimated only by total protein concentration as far as protein fraction is maintained in constant level.
However, for uremic serum, protein fraction is different from normal one, which influences its viscosity. Therefore, the influence of the fraction must also be considered for viscosity estimation.
In the study, new empirical equation for viscosity was introduced with a function of protein fraction as V-factor. The equation was improved through 41 clinical data by CA membrane electrophoresis.
As a result, almost all kind of serum viscosity could be estimated.