High degree of solute removal occurs especially in HDF therapy due to both diffusion and convection. Shortening of therapeutic time may be easily planned in HDF compared with in HD and HF. The nomogram, which was designed for the simplicity of use, gives the conditions for 50% reduction of solute in HDF. For single pass HDF, much larger quantities of solute were removed from the human body water than expected; consequently, recirculating pass HDF was satisfactorily applicable to patients, whose body water were relatively light. Physical model was also devised in expectation of prcving this fact.
