Specific Immunoglobulin Response in Mice Immunized with Porins and Challenged with Salmonella typhi

Praveen SHARMA; Nirmal Kumar GANGULY; Bal Krishan SHARMA; Saroj SHARMA; Rakesh SEHGAL

Specific Immunoglobulin Response in Mice Immunized with Porins and Challenged with Salmonella typhi

Praveen SHARMA, Nirmal Kumar GANGULY, Bal Krishan SHARMA, Saroj SHARMA, Rakesh SEHGAL

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JOURNAL FREE ACCESS

1989 Volume 33 Issue 7 Pages 519-525

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Abstract

Specific antiporin antibody (IgG, IgM, and IgA) response was studied in control, infected, immunized-infected, and immunized mice. The activity of specific IgG immunoglobulins was found to be the highest in immunized and immunized-infected groups in which 87.5% protection had been observed by laboratory potency test in mice; the next-highest activities were those of IgM and IgA immunoglobulins. However, in the infected group the activity of specific IgM and IgG immunoglobulins was almost similar.

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