The hydraulic permeability (Lp) of a hemofiltration (HF) membrane is highly influenced by the proteins in plasma. It is always observed to decrease ultrafiltration rate (UFR) or increase transmembrane pressure (IMP) during HF therapy on chronic renal failure patients. For such a patient, the blood usually tends to be chyliform. The effect of Lipids to Lp of the HF membrane, therefore, was experimentally investigated in this paper.
The correlation coefficient between triglycerol (TG) and in vitro Lp (Lp(G)) was fairly high, that is, 0.9531, and the correlation equation was as follows;
Lp(G)=-0.01916*(TG)+8.7989
The chyliform plasma of HD patients gives higher TG concentration than the normal plasma of HD patients (p<0.01). However, total protein (TP) has more effect on Lp(G) than TG.
Lp(G) may be altered especially by the high TG concentration in plasma.