Using survey data from 564 Japanese workers, we investigate whether family-to-work facilitation (F →WF) influences employee creativity. We also examine the moderating effect of job autonomy and centralization on the relationship between F→WF and creativity. The results show that F→WF, job autonomy, and centralization displayed significant relationships with employee creativity. In addition, the moderating effects of job autonomy and centralization are found. Implications for theory and practice are discussed.