消化器内視鏡の進歩:Progress of Digestive Endoscopy
Online ISSN : 2189-0021
Print ISSN : 0389-9403
症例
除菌終了17カ月後に13CUBT値が陰性化した胃潰瘍の1例
伊月 葉子平川 恒久小野瀬 裕之横瀬 紀夫三宅 一昌津久井 拓香川 隆男坂本 長逸小林 正文
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キーワード: Hp除菌治療, 13CUBT
ジャーナル フリー

1999 年 53 巻 p. 146-147

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This paper reports a 67-year-old man who was diagnosed as having gastric ulcer (stage A1) in January 1995. The ulcer recurred repeatedly despite treatments using PPI and other drugs. H pylori infection was detected by anti-Hp Ig-G antibody (2+) , RUT (+) , microscopy (+) , and the 13CUBT (46.2‰) , so eradication therapy was performed in May 1996. The therapy consisted of a PPI (30mg/day of lansoprazole) , AMPC (1,500mg for 2 weeks) , and CAM (400mg for 2 weeks) . Although the ulcer healed to stage S1 by 4 weeks after completion of therapy, eradication was concluted to have failed because the 13CUBT was result 8.7‰ after 4 weeks and 17.5‰ after 8weeks.
Subsequently, an H2-blocker was administered and the ulcer healed to stage S2 in October 1997 (17 months after eradication therapy) . The 13CUBT value was 1.9‰, and RUT, microscopy, and serum anti-Ig-G antibody were all negative. In this patient, H pylori was considered to have been spontaneously cleared because he did not take medications that could eliminate the organism after the eradication therapy, except for 1,500mg of AMPC for 5 days to treat an acute upper respiratory tract infection.

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© 1999 一般社団法人 日本消化器内視鏡学会 関東支部
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