Magnifying Endoscopic Observation of Duodenal Involvement of Follicular Lymphoma before and after Chemotherapy

Masaya Iwamuro; Hiroyuki Okada; Katsuyoshi Takata; Nobuharu Fujii; Seiji Kawano; Yoshiro Kawahara; Tadashi Yoshino; Kazuhide Yamamoto

doi:10.2169/internalmedicine.54.4390

CASE REPORTS

Magnifying Endoscopic Observation of Duodenal Involvement of Follicular Lymphoma before and after Chemotherapy

Masaya Iwamuro, Hiroyuki Okada, Katsuyoshi Takata, Nobuharu Fujii, Seiji Kawano, Yoshiro Kawahara, Tadashi Yoshino, Kazuhide Yamamoto

Author information

Masaya Iwamuro
Department of Molecular Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Japan
Hiroyuki Okada
Department of Endoscopy, Okayama University Hospital, Japan
Katsuyoshi Takata
Department of Pathology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Japan
Nobuharu Fujii
Department of Hematology and Oncology, Okayama University Hospital, Japan
Seiji Kawano
Department of Endoscopy, Okayama University Hospital, Japan
Yoshiro Kawahara
Department of Endoscopy, Okayama University Hospital, Japan
Tadashi Yoshino
Department of Pathology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Japan
Kazuhide Yamamoto
Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Japan

Keywords: follicular lymphoma, duodenal neoplasms, magnifying endoscopy, rituximab, gastrointestinal lymphoma

JOURNAL OPEN ACCESS

2015 Volume 54 Issue 14 Pages 1741-1745

DOI https://doi.org/10.2169/internalmedicine.54.4390

Details

Abstract

A 60-year-old Japanese man was diagnosed with systemic follicular lymphoma with duodenal, jejunal, and ileal involvement. The duodenal lesion showed typical endoscopic features with multiple whitish granules. Chemotherapy with bendamustine and rituximab was administered, and complete remission was confirmed by CT scanning and positron emission tomography scanning. Although the duodenal granular lesions did not completely disappear, magnifying observation for the remaining lesions showed no evidence of residual lymphoma. Complete remission was pathologically confirmed by biopsy examinations. This case suggests the usefulness of magnifying observation in evaluating the effects of treatment for duodenal follicular lymphoma lesions.

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