The current research examined the moderating role of beliefs in group interdependence on effects of negative meta-stereotypes. The effects of meta-stereotypes among Japanese participants were explored by examining responses toward a fictitious Korean defendant (Study 1), or a real political agenda between Korea and Japan (Study 2), after being exposed to negative views that Koreans might have of Japanese. In addition, the extent to which participants believed in group interdependence between the nations was measured. The results of the two experiments revealed that effects of negative meta-stereotypes were moderated by beliefs in group interdependence. The individuals with higher beliefs in group interdependence responded more favorably toward the outgroup when faced with negative meta-stereotypes, perhaps in an attempt to disconfirm the negative meta-stereotypes. On the other hand, the individuals with lower beliefs in group interdependence reciprocated with unfavorable responses when faced with negative meta-stereotypes.